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Sara Arian, MD, FACOG, MSc

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Dr. Sara Arian (she/her) is a board-certified Reproductive Endocrinologist at Boston IVF. She specializes in all aspects of fertility care.

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Sara Arian, MD, FACOG, MSc

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Biography

Dr. Sara Elizabeth Arian, FACOG, MSc, is a Reproductive Endocrinologist at Boston IVF’s Quincy Fertility Center. She is double board-certified in Obstetrics & Gynecology and Reproductive Endocrinology & Infertility (REI).

She is an expert in all facets of reproductive health and fertility care, including robotic and laparoscopic surgeries. She has a particular interest in fertility preservation for cancer patients and reproductive and fertility-sparing surgeries.

The American Society of Reproductive Medicine (ASRM) has awarded and recognized Dr. Arian for her surgical skills.

Dr. Arian joins us from Baylor College of Medicine and Texas Children’s Hospital Pavilion for Women, where she served as an Assistant Professor of Obstetrics, Gynecology, and Reproductive Sciences. She also served as the Co-Director of the Texas Children’s Hospital Uterine Transplant Program, a board member and Director of REI at Texas Children’s Hospital United States Olympic and Paralympic Women’s Health Committee, and a board member of the Texas Children’s Hospital Clinical Ethics Committee.

She earned a bachelor’s degree at the University of Toronto in Canada, received her MD at the Iran University of Medical Sciences, and completed her Obstetrics, Gynecology, and Reproductive Sciences residency at the University of Texas Health Science Center in Houston and her fellowship in Reproductive Endocrinology & Infertility at the Cleveland Clinic and Baylor College of Medicine. She received her Master's in Clinical Research at Baylor College of Medicine.

Dr. Arian has authored numerous publications in prestigious journals, written several book chapters, and has received multiple awards for her innovative research, including the Society for Reproductive Investigation (SRI) President’s Presenter’s Award for her research in reproductive genetics and the Houston Top Physician and Texas Rising Star Awards.

In addition to her position at Boston IVF, Dr. Arian is a Clinical Instructor at Harvard Medical School, where she teaches and trains BIDMC residents and Boston IVF fellows. Dr. Arian is also a member of several reproductive medicine organizations, including the ASRM, the American College of Obstetricians and Gynecologists (FACOG), the International Society of Fertility Preservation, and the Fertility and Sterility Journal.

Awards

Castle Connolly Top Doctor | 2024-2025
Boston Magazine Top Doctor | 2025
Houstonia Magazine Top Fertility Doctor | 2022
Texas Rising Star Award | 2021-2022
Society for Reproductive Investigation (SRI) President's Presenter's Award | 2019

Interview

Every day I am inspired by my patients’ resilience and perseverance.

Sara Arian, MD, FACOG, MSc

MD Q&A

Have Any Patients Truly Inspired You?
Every day I am inspired by my patients’ resilience and perseverance. Most of them face the challenges of infertility with strength and determination, undergoing numerous diagnostic tests, treatments, and setbacks with unwavering hope. Even when faced with many challenges, they find ways to maintain hope, pursue their dreams of parenthood, and often discover a new sense of purpose in their journey. Sharing their experiences, including difficult moments and all the ups and downs of this emotional rollercoaster, shows a willingness to be vulnerable and connect with others on a deeper level. I truly admire my patient’s emotional strength.

What is Your Favorite Part of Working as a Fertility Specialist?
There are many things I enjoy doing as part of my work/daily life as a fertility specialist:

Helping people overcome difficulties in their fertility journey and helping them start a family and becoming parents. Seeing a positive pregnancy test or meeting a baby born as a result of my work is very rewarding and fulfilling.
Building close relationships with my patients.
Utilizing cutting-edge technology and advancements: the field of reproductive endocrinology and infertility (REI) is constantly evolving and ever-changing. I am passionate about using these advancements to improve patient care and outcomes.
Every day, I enjoy listening to, sharing, counseling, guiding and developing a partnership with my patients throughout their unique journey. My goal is to advocate for each of my patients, empower them with knowledge about their reproductive potential and options, help them regain control of their reproductive health, and instill confidence in the experience and support that myself and my Boston IVF team can provide.

“Find a job you enjoy doing, and you will never have to work a day in your life.”

What Interests you About Research?
Intellectual stimulation and continuous learning: the field of REI offers continuous learning opportunities due to the field's rapid evolution and the need to manage complex medical cases. Fertility research is a dynamic and evolving field with the potential to make a significant positive impact on people's lives. The intersection of scientific advancements, individualized patient care, and ethical discussions shape this field.

How Do You Spend Your Free Time?
I love traveling, spending time with my family, exploring new restaurants and coffee shops, and spinning my Peloton bike.

How Would You Describe Your Personality?
Very vibrant, friendly, outgoing, caring, compassionate, strong communication skills, and a strong commitment to taking great care of my patients, and lifelong learning.

Where is the One Place You'd Like to Visit?
Bora Bora

Publications

Recent Selected Publications

1. Arian SE, Mostafaei S. Response letter to "Some common, fatal flaws in systematic reviews of observational studies". Fertil Steril. 2024 Aug; 122(2):391. PMID: 38657889

2. Arian SE. Reply of the Authors: "Why lab-developed test for endometrial receptivity analysis may have failed to deliver". Fertil Steril. 2024 Jun; 121(6):1079. PMID: 38608870

3. Hessami K, Khatibi A, Arian SE. Response letter to Endometrial receptivity array before frozen embryo transfer cycles: a systematic review and meta-analysis. Fertil Steril. 2023 05; 119(5):892. PMID: 36642306

4. Hessami K, Welch J, Frost A, AlAshqar A, Arian SE, Gough E, Borahay MA. Perioperative opioid dispensing and persistent use after benign hysterectomy: a systematic review and meta-analysis. Am J Obstet Gynecol. 2023 Jul; 229(1):23-32.e3. PMID: 36539027; PMCID: PMC10276170

5. Arian SE, Hessami K, Khatibi A, To AK, Shamshirsaz AA, Gibbons W. Endometrial receptivity array before frozen embryo transfer cycles: a systematic review and meta-analysis. Fertil Steril. 2023 02; 119(2):229-238. PMID: 36414088

6. Hessami K, Norooznezhad AH, Monteiro S, Barrozo ER, Abdolmaleki AS, Arian SE, Zargarzadeh N, Shekerdemian LS, Aagaard KM, Shamshirsaz AA. COVID-19 Pandemic and Infant Neurodevelopmental Impairment: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022 10 03; 5(10):e2238941. PMID: 36306133; PMCID: PMC9617178

7. LePoidevin L, Dunn T, Arian SE, Kaskar K, Schutt A. In vitro fertilization outcomes in VACTERL association (vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies and limb anomalies): report of 2 cases. F S Rep. 2022 Sep; 3(3):280-284. PMID: 36212569; PMCID: PMC9532890

8. Hessami K, Aagaard KM, Castro EC, Arian SE, Nassr AA, Barrozo ER, Seferovic MD, Shamshirsaz AA. Placental Vascular and Inflammatory Findings from Pregnancies Diagnosed with Coronavirus Disease 2019: A Systematic Review and Meta-analysis. Am J Perinatol. 2022 11; 39(15):1643-1653. PMID: 35240710

9. Shamshirsaz AA, Hessami K, Morain S, Afshar Y, Nassr AA, Arian SE, Asl NM, Aagaard K. Intention to Receive COVID-19 Vaccine during Pregnancy: A Systematic Review and Meta-analysis. Am J Perinatol. 2022 04; 39(5):492-500. PMID: 34670322

10. Salmanian B, Arian SE, Shamshirsaz AA. The role of in vitro fertilization-embryo transfer in the development of placenta accreta spectrum. Am J Obstet Gynecol. 2021 10; 225(4):462. PMID: 34144018

11. Arian SE, Erfani H, Yadav GS, Clark S, Gibbons WE, Shamshirsaz AA. Neonatal and maternal outcomes among twin pregnancies stratified by mode of conception in the United States. Fertil Steril. 2021 08; 116(2):514-521. PMID: 33975727

12. Davis AC, Richards EG, Arian SE, Falcone T, Desai N, Yao M, Chiesa-Vottero A, Flyckt R. Diverse Approaches to Ovarian Tissue Cryopreservation Have Equivalent Outcomes in Markers of Tissue Viability. Reprod Sci. 2021 08; 28(8):2129-2135. PMID: 33599949

13. Arian S, Rubin J, Chakchouk I, Sharif M, Mahadevan SK, Erfani H, Shelly K, Liao L, Lorenzo I, Ramakrishnan R, Van den Veyver IB. Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect. Reprod Sci. 2021 07; 28(7):1850-1865. PMID: 33090377; PMCID: PMC8060370

14. Arian SE, Erfani H, Westerfield LE, Buffie A, Nassef S, Gibbons WE, Van den Veyver IB. Prenatal testing in pregnancies conceived by in vitro fertilization with pre-implantation genetic testing. Prenat Diagn. 2020 06; 40(7):846-851. PMID: 32297346

15. Salmanian B, Fox KA, Arian SE, Erfani H, Clark SL, Aagaard KM, Detlefs SE, Aalipour S, Espinoza J, Nassr AA, Gibbons WE, Shamshirsaz AA, Belfort MA, Shamshirsaz AA. In vitro fertilization as an independent risk factor for placenta accreta spectrum. Am J Obstet Gynecol. 2020 10; 223(4):568.e1-568.e5. PMID: 32360847

16. Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, Pooransari P, Ghotbizadeh F, Aalipour S, Soleimani Z, Naemi M, Molaei B, Ahangari R, Salehi M, Oskoei AD, Pirozan P, Darkhaneh RF, Laki MG, Farani AK, Atrak S, Miri MM, Kouchek M, Shojaei S, Hadavand F, Keikha F, Hosseini MS, Borna S, Ariana S, Shariat M, Fatemi A, Nouri B, Nekooghadam SM, Aagaard K. Maternal death due to COVID-19. Am J Obstet Gynecol. 2020 07; 223(1):109.e1-109.e16. PMID: 32360108; PMCID: PMC7187838

17. Arian SE, Flyckt RL, Herman R, Erfani H, Falcone T. Fertility preservation in pediatric female cancer patients. Fertil Steril. 2018 05; 109(5):941. PMID: 29778393

18. Shamshirsaz AA, Bateni ZH, Sangi-Haghpeykar H, Arian SE, Erfani H, Shamshirsaz AA, Abuhamad A, Fox KA, Ramin SM, Moaddab A, Maskatia SA, Salmanian B, Lopez KN, Hosseinzadeh P, Schutt AK, Nassr AA, Espinoza J, Dildy GA, Belfort MA, Clark SL. Cyanotic congenital heart disease following fertility treatments in the United States from 2011 to 2014. Heart. 2018 06; 104(11):945-948. PMID: 29146625

19. Moaddab A, Chervenak FA, Mccullough LB, Sangi-Haghpeykar H, Shamshirsaz AA, Schutt A, Arian SE, Fox KA, Dildy GA, Shamshirsaz AA. Effect of advanced maternal age on maternal and neonatal outcomes in assisted reproductive technology pregnancies. Eur J Obstet Gynecol Reprod Biol. 2017 Sep; 216:178-183. PMID: 28783553

20. Arian SE, Goodman L, Flyckt RL, Falcone T. Ovarian transposition: a surgical option for fertility preservation. Fertil Steril. 2017 Apr; 107(4):e15. PMID: 28238491